Many supplements that once seemed helpful can actually backfire after 50—take kava, for instance, which may quietly strain your liver’s already slower regeneration, or calcium, which could increase your risk of kidney stones and artery calcification when not balanced with other nutrients. And if you’re still loading up on iron, vitamin E, or selenium without checking your current levels, you might be fueling inflammation or increasing your cancer risk—let’s watch the video to see exactly which six supplements you should reconsider now.